August 2019: Youth Mental Health Development

Executive Editor Michael Roy speaks with Thorhildur Halldorsdottir, Ph.D., and Elisabeth Binder, M.D., Ph.D., about their research on predicting depression outcomes in youths and how the interaction between FKBP5, a gene involved in regulating the stress system, and early-life exposure to intimate partner violence affects the physiological response to stress early in life, with consequences for emotional and cognitive development. How polygenic risk scores may be used to identify risk for and symptoms of depression in young people [3:32] The interaction between exposure to stress in early life and emotional and cognitive development [8:05] Key points from each study [10:26] Applying gene-by-environment research to real-world work [14:27] What lies ahead in the study of how genes and the environment interact to influence mental health [16:34] Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Stitcher, or wherever you listen to it. The podcast is now on Spotify. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. Also visit the online edition of this month’s Journal to watch a video of Deputy Editor Daniel S. Pine, M.D., present highlights from the issue. Follow the Journal on Twitter. E-mail us at [email protected]