A cryo–electron microscope accessible to the masses, and tracing the genetics of schizophrenia

Structural biologists rejoiced when cryo–electron microscopy, a technique to generate highly detailed models of biomolecules, emerged. But years after its release, researchers still face long queues to access these machines. Science’s European News Editor Eric Hand walks host Meagan Cantwell through the journey of a group of researchers to create a cheaper, more accessible alternative. Also this week, host Joel Goldberg speaks with psychiatrist and researcher Goodman Sibeko, who worked with the Xhosa people of South Africa to help illuminate genetic details of schizophrenia. Though scientists have examined this subject among Western populations, much less is known about the underlying genetics of people native to Africa. This week’s episode was edited by Podigy. Download a transcript (PDF). Listen to previous podcasts. About the Science Podcast [Image: Jon Mold; Music: Jeffrey Cook]